10,11-trans-dihydroxy-10,11-dihydrocarbamazepine is a dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide substituted by hydroxy groups at positions 10 and 11. It is a metabolite of the drug carbamazepine.
10, 11-Dihydroxycarbamazepine, also called carbamazepine diol, is a metabolite of both carbamazepine and oxcarbazepine. Carbamazepine (CBZ) is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia. Oxcarbazepine is an anticonvulsant and mood-stabilizing drug, used primarily in the treatment of epilepsy. It is also used to treat anxiety and mood disorders, and benign motor tics.
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine.
10-Hydroxycarbazepine is an active metabolite of oxcarbazepine. Oxcarbazepine is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. It is also used to treat anxiety and mood disorders, and benign motor tics. Oxcarbazepine is marketed as Trileptal by Novartis and available in some countries as a generic drug.
An epoxide and metabolite of carbamazepine. Carbamazepine (CBZ) is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia. sigma-aldrich
In one study of long-term efficacy, nortriptyline showed a higher relapse rate in comparison with phenelzine in individuals being treated for depression, possibly due to the metabolite 10-hydroxynortriptyline being produced.
See also NIST Hydroxynortriptyline (an isomer).
11-Hydroxy-Δ9-tetrahydrocannabinol (11-OH-THC) is the main active metabolite of Tetrahydrocannabinol (THC) which is formed in the body after cannabis is consumed. The conversion from THC to 11-OH-THC is relatively high when cannabis is consumed in the form of cannabis edibles and, compared to oral consumption, lower when it is smoked or vaped.
Reference solution: 1 mg in 1 mL methanol. GC RI 1251 (estimated with error: 83). Caymanchem: CAS RN 2338-18-3; C9H11N*HCl=169.7; Purity ≥95%; A crystalline solid; UV max: 210, 266, 272nm. GC/MS 30mx0.32mm, 0.5u Rtx-5MS, 50C-30C/min-300C; RT=5.29min.
2-Aminoindane (2-AI) is a psychoactive drug and research chemical with stimulant properties. It is a rigid pre-analogue [precursalog] of amphetamine and partially substitutes for it in rat discrimination tests.
There are a number of derivatives of 2-aminoindane and its positional isomer 1-aminoindane exist, including:
5-IAI; Aprindine; ETAI; Indanorex; Indantadol; Jimscaline; Ladostigil; MDAI; MDMAI; MMAI.
New Psychoactive Substance (NPS). CAS RN 5807-81-8 (HCl). M.p. 319°C. Legal status: DE: Anlage II; UK: Class B. Caymanchem: C18H21N*HCl=287.8; Purity ≥98%; A crystalline solid. GC/MS 30mx0.32mm, 0.5u Rtx-5MS, 50C-30C/min-300C; RT=8.67min.
Desoxypipradrol, also known as 2-diphenylmethylpiperidine (2-DPMP), acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) developed by Ciba in the 1950s.
GE: (Authorized trade only, not prescriptible).
see Desipramine. GC RI 2564 (estimated with error: 89). MS predicted by CFM(EI): available.
2-hydroxydesipramine is a metabolite of desipramine. Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA). It inhibits the reuptake of norepinephrine and to a lesser extent serotonin. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. It is sold under the brand names Norpramin and Pertofane. Along with other tricyclics, desipramine has found use in treating neuropathic pain.
2-hydroxyimipramine is a metabolite of imipramine. Imipramine (sold as Antideprin, Deprimin, Deprinol, Depsol, Depsonil, Dynaprin, Eupramin, Imipramil, Irmin, Janimine, Melipramin, Surplix, Tofranil), also known as melipramine, is an antidepressant medication, a tricyclic antidepressant of the dibenzazepine group. Imipramine is mainly used in the treatment of major depression and enuresis (inability to control urination). It has also been evaluated for use in panic disorder.
NORTRIPTYLINE is metabolite of AMITRIPTYLINE. CAS RN: Not Available; CAS replaced with PubChem CID.
In one study of long-term efficacy, nortriptyline showed a higher relapse rate in comparison with phenelzine in individuals being treated for depression, possibly due to the metabolite 10-hydroxynortriptyline (an isomer) being produced.